Innovations such as Trapped Ion Mobility (TIMS), smartbeam and scanning lasers for MALDI-MS Imaging that deliver true pixel fidelity, and eXtreme Resolution FTMS (XR) technology capable to reveal Isotopic Fine Structure (IFS) signatures are pushing scientific exploration to new heights. Our mass spectrometry solutions enable scientists to make breakthrough discoveries and gain deeper insights.
Bruker's product lines include the following technologies: timsTOF, MRMS, rapifleX® MALDI-TOF/TOF, UHR-QTOF, Triple Quadrupole, HDX Solution, Toxtyper® and TargetScreener HR. Our industry leading software solutions such as SCiLS™ Lab for MS Imaging, MetaboScape® and Biopharma Compass® are examples for our solutions doing the work for you.
Bruker’s Innovative Mass Spectrometry Solutions
Ion Trap MS
Bruker Daltonics leads the industry in ion trap technology to offer a comprehensive series of ion trap systems meeting a wide range of user needs. Structural confirmation and screening applications in routine labs are also covered through protein identification (ID) and detailed characterization of both small and large molecules.
The amaZon speed series is a true revolution in ion trap technology. This ion trap system is equipped with a dual ion funnel for the highest sensitivity resulting in new analytical levels in mass spectrometry.
Designed to deliver outstanding performance in terms of sensitivity, speed, and dynamic range, our ion trap systems achieve unmatched results even for the most difficult analyses. The amaZon speed ion trap systems can also be equipped with electron transfer dissociation (ETD) technology to facilitate analysis of post translational modifications (PTMs) on proteins or peptides. This potent upgrade makes the ion trap system ideal for PTM analysis work.
ESI-ITMS
Ion Trap MS Instruments
Liquid chromatography
Bruker offers access to a wide variety of high performance liquid chromatography (HPLC) systems. Many sample analysis workflows rely on liquid chromatography separation for its analytical depth. The value and versatility of chromatography analysis is amplified dramatically when coupled to a mass spectrometry (MS) system.
Bruker’s Compass HyStar system is a state-of-the-art software that can be used to configure and control a range of instruments used in liquid chromatography-mass spectrometry (LC-MS). Compatible with HPLC systems from many vendors, Compass HyStar integrates LC-MS data collection and allocates the data to a specified workflow. Subsequent data processing and reporting is facilitated by accessing the workflow, including quantitation, target identification and screening tests. By using Compass HyStar, customers can choose their preferred HPLC vendor and configuration combined with the convenience of a single point of contact for service and support.
LC-MS
LC-MS Connectivity
MALDI Biotyper® - Changing microbiology
The MALDI Biotyper® (MBT) is a microbial identification system based on MALDI-TOF mass spectrometry, allowing unbiased identification of microorganisms within a few minutes down to the species level. The MBT is an easy, rapid, robust, high-throughput, cost-effective and efficient identification technology, ideally suited to microbial laboratories.
Due to its broad applicability, speed of analysis and low sample processing costs, the MBT is ideally suited to the role of microorganism identification. MALDI-TOF MS determines the unique proteomic fingerprint of an organism, and matches characteristic patterns with an extensive reference library to determine the organism´s identity. Continuous expansion of the reference library ensures that a broad range of microorganisms can be identified easily.
Bruker´s state-of-the art MALDI Biotyper® solutions
MALDI-TOF and TOF/TOF MS
The analytical advantages of matrix assisted laser desorption ionization (MALDI) TOF MS have been demonstrated for more than 25 years. With inherent benefits including its speed (time to results) and application flexibility, the convenience and effectiveness of MALDI-TOF MS is magnified by virtue of its low sample volume requirements and broad sample content (salts, buffers) amenability. Dramatic increases in the depth of MALDI analyses have been made routine by intuitive software, and easy automation allows for high throughput solutions.
Bruker’s FLEX series instruments provide reliable results from a market leading technology platform - well-known for outstanding performance, reliability, convenience and innovative design. From rapid screening to comprehensive target characterization, MALDI-TOF MS offers broad utility to meet all laboratory needs. Expert users and beginners can quickly and confidently tap into the analytical power and flexibility of Bruker’s FLEX series MALDI-TOF systems.
MALDI-TOF/TOF
MALDI-TOF and TOF/TOF Instruments
Magnetic Resonance Mass Spectrometry (MRMS)
Bruker’s scimaX® and solariX series instruments are powered by MRMS (Magnetic Resonance Mass Spectrometry) technology. Compared with common FTMS technologies, these instruments feature unmatched eXtreme Resolution (XR) and mass accuracy. This enables routine Isotopic Fine Structure (IFS) analysis for a broad mass range, resulting in unmatched confidence for compound identification.
MRMS
MRMS Instruments
QTOF Mass Spectrometry
Since its first commercial launch 25 years ago, quadrupole time-of-flight (QTOF) mass spectrometry (MS) has revolutionized numerous fields, ranging from biological and pharmaceutical research to clinical toxicology. The unique hybridization of quadrupole and TOF technology resulted in high-resolution, high mass accuracy analysis of all ions simultaneously, which is today used to identify and quantify complex mixtures or unknown compounds.
The MS/MS capabilities of QTOF MS systems enable coupling to both LC and GC systems and Bruker’s expertise provides a variety of innovative instruments. Our powerful, high performance products are specifically designed to meet the rapidly growing needs of customers in the academic, pharmaceutical, industrial, clinical, and applied markets.
QTOF
QTOF MS Instruments
Trapped Ion Mobility Spectrometry (TIMS)
Ion mobility spectrometry (IMS) is a powerful analytical technique that has been widely applied over the last five decades, primarily in chemical physics and analytical chemistry applications. Only relatively recently has the potential of IMS coupled to MS (IMS-MS) been explored for the separation, identification and quantification of peptides and proteins.
TIMSTOF
timsTOF Instruments
MALDI-TOF and TOF/TOF MS
The analytical advantages of matrix assisted laser desorption ionization (MALDI) TOF MS have been demonstrated for more than 25 years. With inherent benefits including its speed (time to results) and application flexibility, the convenience and effectiveness of MALDI-TOF MS is magnified by virtue of its low sample volume requirements and broad sample content (salts, buffers) amenability. Dramatic increases in the depth of MALDI analyses have been made routine by intuitive software, and easy automation allows for high throughput solutions.
Bruker’s FLEX series instruments provide reliable results from a market leading technology platform - well-known for outstanding performance, reliability, convenience and innovative design. From rapid screening to comprehensive target characterization, MALDI-TOF MS offers broad utility to meet all laboratory needs. Expert users and beginners can quickly and confidently tap into the analytical power and flexibility of Bruker’s FLEX series MALDI-TOF systems.
MALDI-TOF/TOF
MALDI-TOF and TOF/TOF Instruments
Software driven mass spectrometry solutions
Our software solutions provide accurate, fast and comprehensive analysis of mass spectrometry data for the relevant applications and research fields. With streamlined integration into the Bruker range of mass spectrometry instrumentation, Bruker software provides the most automated, integrated and powerful solutions in the world.
MS SOFTWARE